Jonny Wilkinson kicked 18 points and tries from Australian duo Matt Giteau and George Smith, and hooker Jean-Charles Orioli, saw them get a bonus point victory.
Clermont moved to third in the table with a 44-20 victory over Grenoble while Racing Metro just edged out Biarritz 13-12 to move fourth.
Second placed side Toulouse had thrashed Bayonne 35-6 away from home on Friday night.
Stade Francais finally got their first victory of the season with a 34-24 victory over Perpignan while Agen won 28-16 in a battle of previously winless sides.
Montpellier are ninth after a 23-15 win in Bordeaux.