Wales have suffered an injury blow ahead of the clash against England after lock Luke Charteris was ruled out with a neck injury.
Veteran lock Marco Bortolami will captain Italy in Saturday's Six Nations game against Ireland in Dublin.
France coach Philippe Saint-Andre has made seven changes to his team for Saturday's RBS 6 Nations clash against Scotland at Murrayfield.
Catalan Dragons' early-season injury crisis has deepened with the loss of hooker Ian Henderson with a broken forearm.
Jonny Wilkinson's Toulon caught fire against Oyonnax as they racked up an astonishing 64-10 victory in their Top 14 clash.
Castleford will need to make history if they are to maintain their perfect start to the 2014 First Utility Super League season.
Leeds captain Kevin Sinfield is a surprise inclusion in the Rhinos' 19-man squad to travel to Perpignan on Friday after initially being ruled out of the game
London Irish have announced the signing of England international Luke Narraway from Perpignan.
Castleford coach Daryl Powell has called on French club Catalan Dragons to cut out the foul play.
Catalan Dragons forward Julian Bousquet has been handed a four-match ban for a dangerous tackle.
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