The Hoops boss made 11 changes to the side which beat Hibernian 2-0 in the Clydesdale Bank Premier League at Easter Road on Sunday for Wednesday night's friendly against Wolves at Parkhead and lost by the same score.
Jamie O'Hara's free-kick after 28 minutes gave the Barclays Premier League club the interval lead, doubled after the break with an own goal by second-half substitute Filip Twardzik, who had come on for Cha Du-ri.
Lennon will now pick a team for the match against the Italian giants - before a game against an Irish select side on Sunday - and he will do so with Europe in mind.
"We are up against really good opposition in Inter Milan in the first game," the Irishman said. "So I am looking to put out a really strong team.
"A good chunk of players who didn't play last night will play in that game. We might look at a different variation in the way we line up. Obviously we are playing against a very good European side so it is good to experiment and see what we can do away from home in Europe in that type of game."