Coventry have released youngsters Shaun Jeffers, Will Roberts, Josh Ruffels and Joe Henderson.
Coventry manager Steven Pressley said his side's points deduction is having a detrimental effect on his players following their 1-1 home draw with Brentford.
Brentford lost ground in the race for automatic promotion as goals a minute either side of half-time saw them draw 1-1 at Coventry.
Coventry will be without Jordan Stewart for the visit of third-placed Brentford.
Coventry host Hartlepool without leading scorer Leon Clarke as they look to put their off-field struggles to one side.
Leon Clarke is a major doubt for Coventry's home clash against Colchester.
Lee Carsley will change Coventry's approach for the visit of promotion rivals Swindon as he looks to turn around City's mediocre home form, although his team
New loan signing Aaron Martin is in contention for his debut while striker Cody McDonald is also back in the frame as Coventry make the crunch trip to sixth
Coventry may be without Richard Wood as they look to exact revenge on Crewe when the two sides meet in league action just three days after their Johnstone's
Coventry shrugged off the loss of manager Mark Robins to win 2-0 at lowly Bury.
Coventry continued their climb up the table with a 2-1 win over Oldham thanks to James Bailey's late strike.
Coventry condemned table-topping Tranmere to only their fifth defeat of the season as Leon Clarke's goal secured a 1-0 win for City.
Coventry scored two injury-time goals to progress to the Johnstone's Paint Trophy Northern Section final with a 3-2 win over Preston.
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