The Spain striker, 27, has one year left on his contract and was dropped from Athletic Bilbao’s opening-day Liga match at home to Real Betis, which Los Leones lost 5-3.
"Tomorrow Llorente will speak about his destination,” Arino Bajo told The Telegraph.
“It is very, very possible he will decide to go to the Premier League. I don’t know the club at the moment but there are two interested. One is in London, and one is in Manchester.”
Llorente scored 29 goals in all competitions for Athletic Club last season, and has reached double figures in La Liga in each of the last five campaigns.