Paris St Germain avoided their first home defeat in over a year when Marko Basa's own goal salvaged a 2-2 draw against Lille.
Emmanuel Riviere scored a late goal as Monaco beat 10-man AC Ajaccio 1-0 to move up to second in Ligue 1 on Sunday.
Round-up: James Rodriguez scored his first Ligue 1 goal to lead Monaco to a 2-0 home victory over Stade Rennes
Lille forward Salomon Kalou struck twice in a 3-0 victory over Stade Reims as they kept their European qualifying hopes alive.
Valencia condemned Lille to their worst ever Champions League campaign with a 1-0 victory in France in Group F.
A brace from Jonas gave Valencia a 2-0 Champions League Group F win at home to Lille.
With a place in the Champions League assured, Lille switch their focus to domestic action as they take on big spending PSG.
Paris Saint-Germain playmaker Javier Pastore says he deserved the criticism he has faced in recent months after some below-par performances.
Montpellier's Younes Belhanda inspired his team to a 2-1 home win against Sochaux as they opened a three-point lead at the top.
Defenders Franck Beria and Aurelien Chedjou are doubtful for Lille's trip to Stade Rennes on Sunday.
Big-spending Paris St Germain started the French league campaign with a humbling home defeat as Lille and Marseille drew.
Marseille midfielder Lucho Gonzalez was taken off during the 2-1 defeat to Lille at the weekend with "muscular problems".
Promoted Brest stayed top of Ligue 1 despite being held to a 1-1 draw at home by Sochaux.
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