Ireland midfielder Aiden McGeady has been dropped from Spartak Moscow's first team for an unspecified period.
Swansea striker Wilfried Bony will be sidelined for "several weeks" after suffering a hamstring injury against Valencia.
Wigan Athletic suffered a heart-breaking 2-1 defeat to Zulte Waregem after an 88th minute goal sunk Owen Coyle’s men.
Tottenham eased the pressure on manager Andre Villas-Boas by winning Group K with a 2-0 win over Norwegian minnows Tromso.
Valencia sealed their place in the last 32 with a 1-0 Group A win against Swansea, who lost Wilfried Bony to injury.
Round-up: Lazio won 2-0 at Legia Warsaw to qualify for the Europa League knockout stages after a tie marred by violence.
Fiorentina played a 0-0 draw away to Pacos Ferreira, so will go head-to-head with Dnipro for leadership of Europa League Group E.
Lazio have qualified for the Europa League knockouts after a 2-0 win away to Legia Warsaw and will go head-to-head with Trabzonspor for top spot.
Polish police detained about 120 Lazio fans after violence broke out before Thursday evening's match against Legia Warsaw.
Wigan boss Owen Coyle fancies a shot at a continental giant and wants his team to earn a place in the knock-out stages.
Tottenham manager Andre Villas-Boas insists he is too thick-skinned to worry about any criticism of his regime.
Pablo Hernandez is desperate to get the chance to feature against former club Valencia in the Europa League.
Michael Laudrup expects Valencia to be a completely different proposition from their September meeting when the sides clash in the Europa League.
Swansea manager Michael Laudrup may have Pablo Hernandez available to face the winger's former club Valencia in the Europa League.
Jermain Defoe became Tottenham's most prolific European striker in a 2-1 win over Sheriff Tiraspol at White Hart Lane.
Manager Andre Villas-Boas urged his Tottenham squad to be inspired by Jermain Defoe's European goalscoring record.