Scunthorpe trio Matt Sparrow, Deon Burton and Niall Canavan are all hoping to overcome injuries in time to face Grimsby in the FA Cup.
Scunthorpe could be without defender Niall Canavan and midfield pair Matt Sparrow and David Syers at Chesterfield.
Scunthorpe midfield pair Matt Sparrow and David Syers are hoping to shake off injuries in time to face York.
Scunthorpe striker Chris Iwelumo is hoping to shake off the effects of illness in time to be included in the squad to face Hartlepool.
Scunthorpe teenager Hakeeb Adelakun is hoping to make his first start for the club at Fleetwood.
Scunthorpe defender Eddie Nolan has joined the club's injured list and misses the home game against Cheltenham.
Southend manager Phil Brown was left infuriated by defeat and the manner of Scunthorpe's winning goal in their 1-0 win.
Brian Laws was a delighted man after watching Chris Iwelumo's second-half header down Southend and secure his Scunthorpe side's first victory since the opening
Chris Iwelumo's second-half header ensured Scunthorpe beat Southend 1-0 to secure their first win since the opening day of the season.
Scunthorpe defender Christian Ribeiro is doubtful for Friday night's game at Southend due to a groin injury.
Former captain Cliff Byrne has rejoined Scunthorpe on a three-month loan ahead of Friday night's game at Southend.
Clive Platt rescued a late point for stuttering Northampton in a 1-1 draw at home to Scunthorpe.
Scunthorpe striker Chris Iwelumo could return to the starting line-up at Northampton following injury.
Brian Laws felt his Scunthorpe side could take plenty of positives from their performance against Sheffield United after taking the Blades to a penalty shoot
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