Emporio Armani Milan's fears of making an early exit from the EuroLeague grew after their defeat at Caja Laboral Vitoria.
At the first US Grand Prix in five years, there are no American drivers, but Mexico's Sergio Perez is something of a local hero.
Former EuroLeague champions Maccabi Tel Aviv and Zalgiris Kaunas saw their perfect starts end in a pulsating sixth round of the preliminary group.
CSKA Moscow spoiled the Turkish party with a 85-58 rout of Besiktas on Friday, as Fenerbahce and Anadolu Efes both won.
Former Chicago Bulls forward Andres Nocioni got a rude awakening on his return to the Euroleague when holders Olympiakos beat Caja Laboral 85-81.
Panathinaikos sealed top spot in EuroLeague Group G with a 68-63 win over Unics Kazan in Russia.
FC Barcelona 70-67 Maccabi Tel Aviv; Zalgiris Kaunas 71-77 Cantù; Unics Kazan 63-68 Panathinaikos; Olimpia Milano 85-72 Ülker
Milan downed Panathinaikos 67-58 at OAKA in Greece but the result was not enough to see the Italian side advance to the play-offs.
Panathinaikos 58-67 Olimpia Milano; Real Madrid 86-65 Unicaja Malaga; Cantù 62-63 FC Barcelona; Maccabi Tel Aviv 70-66 Zalgiris Kaunas
Round-up: CSKA Moscow thumped Galatasaray on the third matchday of the EuroLeague's Top 16 stage.
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